ISSN: 2357-8483
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ISSN: 2357-8483
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Researchers Develop Clinically Validated, Wearable Ultrasound Patch For Continuous Blood Pressure Monitoring
por Erna Olmstead (30-08-2025)
The wearable ultrasound patch builds upon an earlier prototype that was pioneered by the lab of Sheng Xu, a professor within the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at UC San Diego. Researchers re-engineered the patch with two key improvements to enhance its performance for steady blood strain monitoring. First, they packed the piezoelectric transducers closer together, enabling them to supply wider protection so they could higher goal smaller arteries such because the brachial and radial arteries, BloodVitals SPO2 that are more clinically related. Second, they added a backing layer to dampen redundant vibrations from the transducers, resulting in improved signal clarity and monitoring accuracy of arterial walls. In checks, BloodVitals health the gadget produced comparable outcomes to a blood pressure cuff and another clinical system called an arterial line, which is a sensor inserted into an artery to constantly monitor blood stress. While the arterial line is the gold customary for real-time SPO2 tracking blood pressure measurement in intensive care units and operating rooms, it is extremely invasive, limits patient mobility, and may cause pain or discomfort.
The patch gives a easier and measure SPO2 accurately more reliable various, real-time SPO2 tracking as proven in validation assessments performed on patients undergoing arterial line procedures in cardiac catheterization laboratories and intensive care items. Researchers conducted extensive assessments to validate the patch’s security and accuracy. A complete of 117 topics participated in studies that evaluated blood pressure throughout a variety of actions and real-time SPO2 tracking settings. In one set of tests, seven members wore the patch during each day activities comparable to cycling, raising an arm or home SPO2 device leg, performing mental arithmetic, meditating, eating meals and consuming energy drinks. In a larger cohort of eighty five topics, the patch was tested throughout modifications in posture, similar to transitioning from sitting to standing. Results from the patch carefully matched those from blood pressure cuffs in all assessments. The patch’s capability to constantly monitor blood strain was evaluated in 21 patients in a cardiac catheterization laboratory and 4 patients who have been admitted to the intensive care unit after surgical procedure. Measurements from the patch agreed closely with results from the arterial line, showcasing its potential as a noninvasive various.
"A big advance of this work is how thoroughly we validated this know-how, because of the work of our medical collaborators," said Xu. "Blood pressure will be everywhere in the place depending on components like white coat syndrome, masked hypertension, day by day actions or use of treatment, which makes it tough to get an accurate diagnosis or handle treatment. That’s why it was so essential for us to check this system in a large variety of actual-world and clinical settings. The analysis workforce is preparing for large-scale clinical trials and plans to combine machine studying to additional improve the device’s capabilities. Efforts are additionally underway to validate a wireless, battery-powered model for lengthy-term use and seamless integration with current hospital systems. Baiyan Qi, Xinyi Yang, Xiaoxiang Gao, Hao Huang, Xiangjun Chen, Yizhou Bian, Hongjie Hu, Ray S. Wu, Wentong Yue, Mohan Li, Chengchangfeng Lu, Ruotao Wang, Siyu Qin, Isac Thomas, Benjamin Smarr, Erik B. Kistler, Belal Al Khiami, Irene Litvan and Sheng Xu, UC San Diego; and Esra Tasali and Theodore Karrison, The University of Chicago.
Issue date 2021 May. To realize highly accelerated sub-millimeter resolution T2-weighted functional MRI at 7T by creating a three-dimensional gradient and spin echo imaging (GRASE) with internal-volume selection and variable flip angles (VFA). GRASE imaging has disadvantages in that 1) k-house modulation causes T2 blurring by limiting the number of slices and 2) a VFA scheme results in partial success with substantial SNR loss. In this work, accelerated GRASE with controlled T2 blurring is developed to enhance a point unfold perform (PSF) and temporal sign-to-noise ratio (tSNR) with a lot of slices. Numerical and experimental research have been carried out to validate the effectiveness of the proposed technique over regular and VFA GRASE (R- and V-GRASE). The proposed methodology, while achieving 0.8mm isotropic decision, purposeful MRI in comparison with R- and V-GRASE improves the spatial extent of the excited volume as much as 36 slices with 52% to 68% full width at half most (FWHM) reduction in PSF but roughly 2- to 3-fold imply tSNR improvement, thus resulting in increased Bold activations.